Ultra-low temperature refrigerating gun It is a space cold isolation guidance technology. It was once the world's most famous (almost the only) ultra-low temperature frozen medical equipment, limited production and sales, and also represents the highest level of refrigeration engineering.
The ultra-low temperature refrigerating gun is a kind of physical therapy equipment, which uses ultra-low temperature freezing to act on the diseased tissue, so that the diseased tissue is necrotic and shedding, so as to achieve the purpose of treatment.
At present, the refrigerant used in the ultra-low temperature refrigerating gun is mainly nitrous oxide, which is a colorless, odorless, transparent liquid with a temperature of about -196 °C. The main mechanism of treatment is sudden cooling, which causes ice crystals to form inside and outside the tissue cells, and the structure is broken and lysed; at the same time, the low temperature causes cell dehydration, electrolyte concentration, pH change, protein denaturation, cell metabolism and death. Although there are many kinds of cryogens commonly used in clinical practice, the therapeutic mechanism is the same, that is, freezing can form crystals inside and outside the tumor cells, causing mechanical damage of the cells themselves, and the intracellular and extracellular osmotic pressure and pH value also change, electrolyte disorder, The lipoproteins of the cell membrane are also denatured, eventually leading to destruction of tumor cells. At the same time, the local blood stagnant, forming a large area of ??capillary embolism, microcirculation is also destroyed, leading to ischemia, which is another cause of tumor cell death.
Indications: internal hemorrhoids, mixed hemorrhoids, anal fissure, anal fistula, cervical erosion, rectal cancer and other diseases.
Cryopreservation of cryopreservation can be tolerated by men, women and children. It does not require anesthesia. There is a degree of pain in the treatment and it may last for several hours. The affected area begins to edema 1 hour after treatment, followed by blisters, and a few will have blood. Blisters, about 1 to 2 weeks of scarring, the molting of the skin naturally falls off, the diseased tissue is removed, and generally no scar is left.
Contraindications for cryopreservation: severe cold urticaria, cryoglobulinemia, Raynaud's disease, and a few elderly, frail, and intolerant to cryotherapy. Diabetes patients with lower extremity blood circulation disorders, such as cryotherapy in the lower leg and foot, often form chronic ulcers that have not healed for a long time, should be used with caution.
The treatment time of ultra-low temperature cryostat also depends on the size of the lesion, which is usually completed in 1 to 5 minutes. Clinically, rectal tumor treatment can reach more than 80% of the maximum freezing effect in 15-30 minutes.
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